- Trials with a EudraCT protocol (25)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
25 result(s) found for: Synovial Sheath.
Displaying page 1 of 2.
EudraCT Number: 2020-003275-17 | Sponsor Protocol Number: AMB-051-01 | Start Date*: 2021-04-23 | |||||||||||
Sponsor Name:AmMax Bio., Inc. | |||||||||||||
Full Title: An Adaptive, Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of Intra-articular AMB-05X Injections in Subjects with Tenosynovial Giant Cell Tumor ... | |||||||||||||
Medical condition: Tenosynovial Giant Cell Tumor of the Knee | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: PL (Ongoing) NL (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2020-004870-22 | Sponsor Protocol Number: AMB-051-02 | Start Date*: 2021-02-24 | |||||||||||
Sponsor Name:AmMax Bio., Inc. | |||||||||||||
Full Title: A Phase 2, Adaptive, Open-Label, Multiple-Dose, Dose-Escalation Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Intravenous AMB-05X in Subjects with Tenosynovial Giant... | |||||||||||||
Medical condition: Tenosynovial Giant Cell Tumor | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) PL (Ongoing) NL (Completed) CZ (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-001134-33 | Sponsor Protocol Number: 012329 | Start Date*: 2019-06-18 | |||||||||||
Sponsor Name:Aarhus University Hospital | |||||||||||||
Full Title: Does repeated administration of cefuroxime after orthopedic surgery provide a better prophylactic profile regarding postoperativ infection than a single administration of preoperative antimicrobia... | |||||||||||||
Medical condition: Orthopedic infections. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2015-002469-41 | Sponsor Protocol Number: EZH-202 | Start Date*: 2016-04-18 | |||||||||||||||||||||||||||||||||||||||||
Sponsor Name:Epizyme, Inc. | |||||||||||||||||||||||||||||||||||||||||||
Full Title: A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects with INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma | |||||||||||||||||||||||||||||||||||||||||||
Medical condition: Cohort 1: Rhabdoid tumors (malignant rhabdoid tumors, rhabdoid tumors of the kidney, atypical teratoid rhabdoid tumors, and selected tumors Cohort 2: Relapsed/refractory synovial sarcoma with SS18... | |||||||||||||||||||||||||||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) BE (Completed) FR (Completed) IT (Ongoing) | |||||||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-004984-35 | Sponsor Protocol Number: EZH-501 | Start Date*: 2016-08-03 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sponsor Name:Epizyme, Inc. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Full Title: Tazemetostat Rollover Study (TRuST): An Open-Label, Rollover Study | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Medical condition: Subjects will receive tazemetostat as dictated in their antecedent study. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial protocol: FR (Ongoing) PL (Ongoing) BE (Completed) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2015-002468-18 | Sponsor Protocol Number: EZH-102 | Start Date*: 2016-02-19 | |||||||||||||||||||||||||||||||||||||||||
Sponsor Name:Epizyme, Inc. | |||||||||||||||||||||||||||||||||||||||||||
Full Title: A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects with Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma | |||||||||||||||||||||||||||||||||||||||||||
Medical condition: Atypical teratoid rhabdoid tumor (ATRT), Malignant rhabdoid tumor (MRT), Rhabdoid tumor of kidney (RTK), selected tumors with rhabdoid features. Epithelioid sarcoma, Epithelioid malignant peripher... | |||||||||||||||||||||||||||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18 | Gender: Male, Female | ||||||||||||||||||||||||||||||||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) DK (Completed) DE (Completed) NL (Completed) IT (Completed) | |||||||||||||||||||||||||||||||||||||||||||
Trial results: View results |
EudraCT Number: 2020-000192-20 | Sponsor Protocol Number: PL3397-A-U4003 | Start Date*: 2020-07-22 | |||||||||||
Sponsor Name:DAIICHI SANKYO, INC. | |||||||||||||
Full Title: A Phase 4, multicenter study to evaluate the discontinuation and re treatment in subjects with tenosynovial giant cell tumor (TGCT) previously treated with pexidartinib | |||||||||||||
Medical condition: Tenosynovial giant cell tumor (TGCT) is a group of neoplasms including pigmented villonodular synovitis (PVNS) and giant cell tumor of the tendon sheath (GCT-TS) | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: HU (Completed) NL (Completed) IT (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2021-003762-13 | Sponsor Protocol Number: NIO-0002 | Start Date*: 2022-07-05 |
Sponsor Name: Narodowy Instytut Onkologii im. Marii Skłodowskiej Curie – Państwowy Instytut Badawczy (NIO-PIB) | ||
Full Title: PHASE 1B/2 STUDY OF LIPOSOMAL ANNAMYCIN (L-ANNAMYCIN) IN PATIENTS WITH PREVIOUSLY TREATED SOFT-TISSUE SARCOMAS WITH PULMONARY METASTASES (ANNA-SARC) | ||
Medical condition: soft tissue sarcomas | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: PL (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2022-000101-28 | Sponsor Protocol Number: AMB-051-07 | Start Date*: 2022-12-08 | |||||||||||
Sponsor Name:AmMax Bio, Inc. | |||||||||||||
Full Title: A Phase 2, Open-Label, Adaptive, Dose-Ranging Study with Long-Term Extension to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of Intra-articular AMB-05X Injections in Subjects w... | |||||||||||||
Medical condition: Tenosynovial Giant Cell Tumor | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Trial now transitioned) IT (Prematurely Ended) PL (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2013-003486-34 | Sponsor Protocol Number: 39132 | Start Date*: 2013-11-04 | |||||||||||
Sponsor Name:Knowledge Centre for Rheumatology and Back Diseases | |||||||||||||
Full Title: Systemic versus ultrasound-guided local glucocorticoid treatment, among rheumatoid arthritis patients with tenosynovitis - a randomized double blind study | |||||||||||||
Medical condition: | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2019-003034-16 | Sponsor Protocol Number: GEIS-74 | Start Date*: 2022-10-06 | |||||||||||
Sponsor Name:Grupo Español de Investigación en Sarcomas (GEIS) | |||||||||||||
Full Title: Phase I/II randomized trial of LB-100 plus doxorubicin vs. doxorubicin alone in first line of advanced soft tissue sarcomas | |||||||||||||
Medical condition: Advanced/metastatic soft tissue sarcoma (undifferentiated pleomorphic sarcoma, leiomyosarcoma, myxoid and hypercellular myxoid liposarcoma, myxofibrosarcoma, NOS sarcoma, synovial sarcoma, fibrosar... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2007-005294-60 | Sponsor Protocol Number: CRAD001C24114 | Start Date*: Information not available in EudraCT | |||||||||||
Sponsor Name:Novartis Pharma GmbH | |||||||||||||
Full Title: Multicenter, triple-arm, single-stage, phase II trial to determine the preliminary efficacy and safety of RAD001 in patients with histological evidence of progressive or metastatic bone or soft tis... | |||||||||||||
Medical condition: histological evidence of progressive or metastatic bone or soft tissue sarcomas | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) IT (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2004-001108-11 | Sponsor Protocol Number: EORTC protocol 62033 | Start Date*: 2004-11-08 | |||||||||||
Sponsor Name:European Organisation for the Research and Treatment of Cancer | |||||||||||||
Full Title: A phase II study of intravenous TZT-1027, administered weekly times two, every three weeks, to patients with advanced or metastatic soft tissue sarcomas (STS) with prior exposure to doxorubicin-bas... | |||||||||||||
Medical condition: Soft Tissue Sarcoma (STS) is a rare group of heterogeneous mesenchymal cancers originating from connective tissue. There are multiple histological subtypes of STS. At present all these subtypes are... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2020-002777-95 | Sponsor Protocol Number: 2020STSNeoadjuvant | Start Date*: 2020-10-29 | |||||||||||
Sponsor Name:Oslo University Hospital | |||||||||||||
Full Title: Sequential neoadjuvant ifosfamide and doxorubicin in localized high-grade soft tissue sarcoma of extremities and trunk wall | |||||||||||||
Medical condition: Soft Tissue Sarcoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: NO (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2005-004272-20 | Sponsor Protocol Number: E7389-E044-207 | Start Date*: 2006-10-23 | |||||||||||
Sponsor Name:Eisai Limited | |||||||||||||
Full Title: Phase II Study of E7389 Administered as an IV Infusion Day 1 and 8 every 3 Weeks in Pretreated Patients with Advanced and/or Metastatic Soft Tissue Sarcoma Protocol Version 5.0 (2010-01-27) | |||||||||||||
Medical condition: Advanced and/or metastatic soft tissue sarcoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: BE (Completed) DE (Completed) DK (Completed) FR (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2014-001549-26 | Sponsor Protocol Number: TRASTS | Start Date*: 2014-11-03 |
Sponsor Name:GEIS | ||
Full Title: Phase I-II prospective trial, multicenter, open label, exploring the combination of Trabectedin plus Radiotherapy in Soft Tissue Sarcoma patients. | ||
Medical condition: Soft Tissue Sarcoma | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: ES (Ongoing) IT (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2021-001186-20 | Sponsor Protocol Number: GEIS-83 | Start Date*: 2021-10-22 |
Sponsor Name:GRUPO ESPAÑOL DE INVESTIGACIÓN EN SARCOMAS | ||
Full Title: Phase Ib/II multicohort trial of different schemes of PM14 in monotherapy and in combination with radiotherapy in soft tissue sarcomas and other solid tumors | ||
Medical condition: Advanced soft tissue sarcoma and other solid tumors | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: ES (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2011-003145-17 | Sponsor Protocol Number: TH-CR-406/SARC021 | Start Date*: 2012-02-28 | |||||||||||
Sponsor Name:Threshold Pharmaceuticals, Inc. | |||||||||||||
Full Title: A Randomized Phase 3, Multicenter, Open-Label Study Comparing TH-302 in Combination with Doxorubicin vs. Doxorubicin Alone in Subjects with Locally Advanced Unresectable or Metastatic Soft Tissue S... | |||||||||||||
Medical condition: Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma | |||||||||||||
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Population Age: Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: ES (Completed) DE (Completed) HU (Completed) PL (Prematurely Ended) BE (Completed) IT (Completed) AT (Prematurely Ended) DK (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2006-001861-40 | Sponsor Protocol Number: BRTA-0100-015 (EORTC 62061) | Start Date*: 2006-09-21 | |||||||||||
Sponsor Name:SYSTEMS MEDICINE, LLC | |||||||||||||
Full Title: Randomized phase II study of brostallicin (PNU-166196A) versus doxorubicin as first line chemotherapy in patients with advanced or metastatic soft tissue sarcoma | |||||||||||||
Medical condition: Advanced or metastatic soft tissue sarcoma. | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: BE (Completed) DE (Completed) GB (Completed) NL (Completed) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2011-004168-30 | Sponsor Protocol Number: STS001 | Start Date*: 2012-08-07 | |||||||||||
Sponsor Name:Hannover Medical School | |||||||||||||
Full Title: A randomized phase II trial comparing pazopanib with doxorubicin as first line treatment in elderly patients with metastatic or advanced soft tissue sarcoma | |||||||||||||
Medical condition: Metastatic or advanced soft tissue sarcoma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) BE (Completed) | |||||||||||||
Trial results: View results |
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